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 What Is Piriformis Syndrome? Symptoms Causes Risk factors Diagnosis Treatment Prevention Outlook Overview You may have heard of sciatica, a unexciting ache that starts in the buttocks and runs the length of one or both legs. Sciatica is usually caused by pressure or irritation of nerves in the demean verification. One condition that causes pressure in version to those nerves is called piriformis syndrome. The piriformis is a muscle that extends from the front of the sacrum. Thats the triangle-shaped bone together in the middle of your two hipbones in your pelvis. The muscle extends across the sciatic nerve to the peak of the femur. The femur is the large bone in your upper leg. The piriformis helps the thigh modify side to side. A piriformis muscle spasm can put pressure on the sciatic nerve and cause symptoms. The result is piriformis syndrome. Symptoms of piriformis syndrome Sciatica is the main symptom of piriformis syndrome. You may experience others, however. Often the discomfort